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Joseph Junewick, MD FACR
over 9 years ago
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ARSt Case Repository

Osteopoikilosis - Adult

Case Detail

Anatomy: Musculoskeletal
Joseph Junewick, MD FACR
Diagnostic Category: Developmental or Congenital
Created: over 6 years ago
Updated: over 6 years ago
Modality/Study Types: CR
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37 y/o male with abdominal pain

Case Images




Innumerable small round and oval shaped subcentimeter foci of increased in the pelvis and hips


Osteopoikilosis is a rare, typically asymptomatic, benign bone dysplasia. It is typically found incidentally, and equally found in both sexes. Overall incidence is about 1:50,000. An autosomal dominant inheritance pattern has been suggested. The lesions are found most frequently in metaphyses and epiphyses of long bones and in the scapula, pelvis, and wrist and tarsal bones.

Very uncommonly they can be associated with pain, and extremely rarely, a few cases have been reported with malignant transformation with osteosarcoma and chondrosarcoma.

Osteopoikilosis lesions do not typically show uptake on bone scan, but in some cases can. Main radiologic differential dignosis includes osteoblastic metastases and mastocytosis, but usually the findings in osteopoikilosis are so typical there is no additional diagnosis to seriously consider.


Clinical Medicine Insights: Arthritis and Muskuloskeletal Disorders 2011; 4: 29-32


DJ Mulligan, MD

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