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Renal Cell Carcinoma
Case Detail
| Anatomy: Genitourinary |
 Joseph Junewick, MD FACR |
| Diagnostic Category: Neoplasia Malignant |
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| Created: over 3 years ago |
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| Updated: over 2 years ago |
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| Tags:
PEDS
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| Modality/Study Types:
US
CT
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Activities:  PDF  ImageJA |
History
7 year old female with remote history of neuroblastoma presenting for surveillance CT.
Case Images
Diagnosis
Renal cell carcinoma
Clinical Notes
Ultrasound was performed after CT.
Findings
CT- peripheral, round, ill-defined, hypodense right renal lesion.
US – round hyperechoic (solid) lesion.
Discussion
Second malignancies occur in 13-25% of children, usually 15 -19 years after treatment of the primary malignancy. Most second malignancies are sarcomas, leukemia or lymphoma. The etiology may be related to genetic cancer predisposition or therapy. Second malignancies with neuroblastoma is more common when the diagnosis of neuroblastoma is made before 1 year of age but is also associated with radiation therapy and the use of alkylating agents.
Reference
Donnelly LF, et al. Renal cell carcinoma after therapy of neuroblastoma. AJR 1996; 167:915-917.